| 2022-01-15 12:30:0001/15/2022 | London Knights  | 28 - 41 |  Baltimore Vultures | N/A |
| 2022-01-15 13:05:0001/15/2022 | Los Angeles Lycans  | 31 - 28 |  Charleston Predators | N/A |
| 2022-01-15 14:45:0001/15/2022 | Arizona Scorpions  | 30 - 14 |  Tulsa Desperados | N/A |
| 2022-01-15 15:15:0001/15/2022 | Sioux Falls Sparrows  | 12 - 34 |  Louisiana Revolution | N/A |
| 2022-01-15 19:30:0001/15/2022 | Vancouver Legion  | 42 - 37 |  Carolina Skyhawks | N/A |
| 2022-01-15 19:50:0001/15/2022 | St. Louis Gladiators  | 31 - 27 |  Las Vegas Fury | N/A |
| 2022-01-16 13:00:0001/16/2022 | Florida Storm  | 17 - 24 |  San Diego Mavericks | N/A |
| 2022-01-16 13:35:0001/16/2022 | Houston Hyenas  | 15 - 20 |  D.C. Dragons | N/A |
| 2022-01-16 15:10:0001/16/2022 | Jacksonville Kings  | 34 - 27 |  Portland Fleet | N/A |
| 2022-01-16 15:45:0001/16/2022 | Atlanta Swarm  | 30 - 24 |  Denver Nightwings | N/A |
| 2022-01-16 18:00:0001/16/2022 | Mexico City Aztecs  | 41 - 38 |  Fort Worth Toros | N/A |
| 2022-01-16 18:20:0001/16/2022 | Queen City Corsairs  | 17 - 35 |  Lone Star Glory | N/A |
| 2022-01-22 12:30:0001/22/2022 | Lone Star Glory | 31 - 27 | London Knights | N/A |
| 2022-01-22 13:05:0001/22/2022 | Tulsa Desperados | 20 - 45 | Las Vegas Fury | N/A |
| 2022-01-22 14:45:0001/22/2022 | Carolina Skyhawks | 36 - 25 | San Diego Mavericks | N/A |
| 2022-01-22 15:15:0001/22/2022 | Los Angeles Lycans | 24 - 30 | Vancouver Legion | N/A |
| 2022-01-22 17:30:0001/22/2022 | Louisiana Revolution | 17 - 31 | Denver Nightwings | N/A |
| 2022-01-22 17:50:0001/22/2022 | Baltimore Vultures | 27 - 6 | Houston Hyenas | N/A |
| 2022-01-24 14:30:0001/24/2022 | Jacksonville Kings | 27 - 26 | Charleston Predators | N/A |
| 2022-01-24 14:50:0001/24/2022 | Sioux Falls Sparrows | 23 - 20 | St. Louis Gladiators | N/A |
| 2022-01-24 16:30:0001/24/2022 | Arizona Scorpions | 13 - 20 | Atlanta Swarm | N/A |
| 2022-01-24 16:50:0001/24/2022 | Mexico City Aztecs | 22 - 32 | Queen City Corsairs | N/A |
| 2022-01-24 18:30:0001/24/2022 | Portland Fleet | 21 - 33 | Florida Storm | N/A |
| 2022-01-24 18:50:0001/24/2022 | D.C. Dragons | 27 - 24 | Fort Worth Toros | N/A |
| 2022-01-29 12:00:0001/29/2022 | Denver Nightwings | 39 - 36 | Sioux Falls Sparrows | N/A |
| 2022-01-29 12:20:0001/29/2022 | D.C. Dragons | 52 - 41 | Lone Star Glory | N/A |
| 2022-01-29 14:30:0001/29/2022 | Vancouver Legion | 28 - 14 | Jacksonville Kings | N/A |
| 2022-01-29 15:00:0001/29/2022 | Baltimore Vultures | 44 - 10 | Fort Worth Toros | N/A |
| 2022-01-29 16:45:0001/29/2022 | London Knights | 23 - 31 | Mexico City Aztecs | N/A |
| 2022-01-29 17:15:0001/29/2022 | Tulsa Desperados | 27 - 13 | Louisiana Revolution | N/A |
| 2022-01-30 13:00:0001/30/2022 | Queen City Corsairs | 34 - 47 | Houston Hyenas | N/A |
| 2022-01-30 13:20:0001/30/2022 | St. Louis Gladiators | 27 - 13 | Atlanta Swarm | N/A |
| 2022-01-30 15:00:0001/30/2022 | Charleston Predators | 23 - 20 | Portland Fleet | N/A |
| 2022-01-30 15:20:0001/30/2022 | Carolina Skyhawks | 12 - 35 | Florida Storm | N/A |
| 2022-01-30 17:00:0001/30/2022 | San Diego Mavericks | 28 - 17 | Los Angeles Lycans | N/A |
| 2022-01-30 17:20:0001/30/2022 | Las Vegas Fury | 27 - 26 | Arizona Scorpions | N/A |
| 2022-02-05 14:30:0002/05/2022 | Fort Worth Toros | 22 - 26 | Queen City Corsairs | N/A |
| 2022-02-05 15:05:0002/05/2022 | Vancouver Legion | 23 - 26 | Charleston Predators | N/A |
| 2022-02-05 16:45:0002/05/2022 | Florida Storm | 24 - 10 | Los Angeles Lycans | N/A |
| 2022-02-05 17:15:0002/05/2022 | Mexico City Aztecs | 23 - 45 | D.C. Dragons | N/A |
| 2022-02-06 19:00:0002/06/2022 | Portland Fleet | 21 - 31 | Carolina Skyhawks | N/A |
| 2022-02-06 19:20:0002/06/2022 | Denver Nightwings | 36 - 38 | Tulsa Desperados | N/A |
| 2022-02-06 21:00:0002/06/2022 | Sioux Falls Sparrows | 29 - 17 | Las Vegas Fury | N/A |
| 2022-02-06 21:20:0002/06/2022 | Louisiana Revolution | 30 - 10 | Arizona Scorpions | N/A |
| 2022-02-12 14:30:0002/12/2022 | Mexico City Aztecs | 27 - 41 | Baltimore Vultures | N/A |
| 2022-02-12 15:05:0002/12/2022 | St. Louis Gladiators | 20 - 23 | Denver Nightwings | N/A |
| 2022-02-12 16:45:0002/12/2022 | Louisiana Revolution | 28 - 20 | Atlanta Swarm | N/A |
| 2022-02-12 17:15:0002/12/2022 | Lone Star Glory | 25 - 21 | Houston Hyenas | N/A |
| 2022-02-14 19:00:0002/14/2022 | Fort Worth Toros | 27 - 38 | London Knights | N/A |
| 2022-02-14 19:20:0002/14/2022 | Carolina Skyhawks | 34 - 37 | Jacksonville Kings | N/A |
| 2022-02-14 21:00:0002/14/2022 | Tulsa Desperados | 22 - 32 | Sioux Falls Sparrows | N/A |
| 2022-02-14 21:20:0002/14/2022 | Portland Fleet | 34 - 47 | San Diego Mavericks | N/A |
| 2022-02-19 14:30:0002/19/2022 | Houston Hyenas | 16 - 20 | Fort Worth Toros | N/A |
| 2022-02-19 15:00:0002/19/2022 | Denver Nightwings | 34 - 37 | Arizona Scorpions | N/A |
| 2022-02-19 16:45:0002/19/2022 | San Diego Mavericks | 23 - 30 | Charleston Predators | N/A |
| 2022-02-19 17:15:0002/19/2022 | Las Vegas Fury | 21 - 33 | Louisiana Revolution | N/A |
| 2022-02-20 17:00:0002/20/2022 | London Knights | 38 - 31 | D.C. Dragons | N/A |
| 2022-02-20 17:20:0002/20/2022 | Atlanta Swarm | 20 - 19 | Sioux Falls Sparrows | N/A |
| 2022-02-20 19:00:0002/20/2022 | Lone Star Glory | 28 - 31 | Mexico City Aztecs | N/A |
| 2022-02-20 19:20:0002/20/2022 | Tulsa Desperados | 31 - 17 | St. Louis Gladiators | N/A |
| 2022-02-20 21:00:0002/20/2022 | Florida Storm | 24 - 41 | Vancouver Legion | N/A |
| 2022-02-20 21:20:0002/20/2022 | Jacksonville Kings | 16 - 45 | Los Angeles Lycans | N/A |
| 2022-02-21 19:15:0002/21/2022 | Baltimore Vultures | 26 - 20 | Queen City Corsairs | N/A |
| 2022-02-26 14:30:0002/26/2022 | Baltimore Vultures | 34 - 20 | Lone Star Glory | N/A |
| 2022-02-26 15:00:0002/26/2022 | Arizona Scorpions | 29 - 16 | St. Louis Gladiators | N/A |
| 2022-02-26 16:45:0002/26/2022 | Charleston Predators | 34 - 26 | Florida Storm | N/A |
| 2022-02-26 17:15:0002/26/2022 | D.C. Dragons | 38 - 30 | Queen City Corsairs | N/A |
| 2022-02-27 19:00:0002/27/2022 | Los Angeles Lycans | 34 - 31 | Carolina Skyhawks | N/A |
| 2022-02-27 19:20:0002/27/2022 | San Diego Mavericks | 7 - 28 | Jacksonville Kings | N/A |
| 2022-02-27 21:00:0002/27/2022 | Atlanta Swarm | 6 - 52 | Las Vegas Fury | N/A |
| 2022-02-27 21:20:0002/27/2022 | Portland Fleet | 30 - 38 | Vancouver Legion | N/A |
| 2022-02-28 19:15:0002/28/2022 | London Knights | 40 - 48 | Houston Hyenas | N/A |
| 2022-03-05 14:30:0003/05/2022 | Queen City Corsairs | 33 - 31 | Arizona Scorpions | N/A |
| 2022-03-05 15:00:0003/05/2022 | Sioux Falls Sparrows | 31 - 21 | D.C. Dragons | N/A |
| 2022-03-05 16:45:0003/05/2022 | Lone Star Glory | 27 - 23 | Los Angeles Lycans | N/A |
| 2022-03-05 17:15:0003/05/2022 | Fort Worth Toros | 24 - 30 | Vancouver Legion | N/A |
| 2022-03-06 19:00:0003/06/2022 | Denver Nightwings | 28 - 36 | London Knights | N/A |
| 2022-03-06 19:20:0003/06/2022 | Mexico City Aztecs | 31 - 20 | Portland Fleet | N/A |
| 2022-03-06 21:00:0003/06/2022 | Carolina Skyhawks | 14 - 22 | Louisiana Revolution | N/A |
| 2022-03-06 21:20:0003/06/2022 | Charleston Predators | 17 - 31 | Tulsa Desperados | N/A |
| 2022-03-12 14:30:0003/12/2022 | Jacksonville Kings | 14 - 31 | Atlanta Swarm | N/A |
| 2022-03-12 15:00:0003/12/2022 | Fort Worth Toros | 40 - 34 | San Diego Mavericks | N/A |
| 2022-03-12 16:45:0003/12/2022 | Vancouver Legion | 31 - 27 | Mexico City Aztecs | N/A |
| 2022-03-12 17:15:0003/12/2022 | Portland Fleet | 10 - 12 | Lone Star Glory | N/A |
| 2022-03-12 19:00:0003/12/2022 | Louisiana Revolution | 15 - 0 | Charleston Predators | N/A |
| 2022-03-12 19:20:0003/12/2022 | Sioux Falls Sparrows | 21 - 31 | Baltimore Vultures | N/A |
| 2022-03-13 17:00:0003/13/2022 | London Knights | 34 - 28 | Las Vegas Fury | N/A |
| 2022-03-13 17:20:0003/13/2022 | Tulsa Desperados | 27 - 17 | Carolina Skyhawks | N/A |
| 2022-03-13 21:00:0003/13/2022 | D.C. Dragons | 17 - 30 | Denver Nightwings | N/A |
| 2022-03-13 21:20:0003/13/2022 | Houston Hyenas | 29 - 22 | Los Angeles Lycans | N/A |
| 2022-03-14 19:15:0003/14/2022 | St. Louis Gladiators | 17 - 30 | Florida Storm | N/A |
| 2022-03-19 12:00:0003/19/2022 | Jacksonville Kings | 20 - 7 | Tulsa Desperados | N/A |
| 2022-03-19 12:20:0003/19/2022 | Los Angeles Lycans | 14 - 46 | Fort Worth Toros | N/A |
| 2022-03-19 14:30:0003/19/2022 | Denver Nightwings | 38 - 56 | Baltimore Vultures | N/A |
| 2022-03-19 15:00:0003/19/2022 | Charleston Predators | 32 - 10 | Carolina Skyhawks | N/A |
| 2022-03-19 16:45:0003/19/2022 | Atlanta Swarm | 13 - 19 | St. Louis Gladiators | N/A |
| 2022-03-19 17:15:0003/19/2022 | Houston Hyenas | 48 - 35 | Portland Fleet | N/A |
| 2022-03-20 17:00:0003/20/2022 | D.C. Dragons | 22 - 21 | Arizona Scorpions | N/A |
| 2022-03-20 17:20:0003/20/2022 | Las Vegas Fury | 35 - 41 | Queen City Corsairs | N/A |
| 2022-03-20 19:00:0003/20/2022 | Lone Star Glory | 34 - 44 | Vancouver Legion | N/A |
| 2022-03-20 19:20:0003/20/2022 | London Knights | 27 - 36 | Sioux Falls Sparrows | N/A |
| 2022-03-20 21:00:0003/20/2022 | Florida Storm | 19 - 20 | Louisiana Revolution | N/A |
| 2022-03-20 21:20:0003/20/2022 | San Diego Mavericks | 31 - 47 | Mexico City Aztecs | N/A |
| 2022-03-26 14:30:0003/26/2022 | Arizona Scorpions | 13 - 23 | London Knights | N/A |
| 2022-03-26 15:00:0003/26/2022 | St. Louis Gladiators | 17 - 31 | Jacksonville Kings | N/A |
| 2022-03-26 16:45:0003/26/2022 | Vancouver Legion | 21 - 20 | Los Angeles Lycans | N/A |
| 2022-03-26 17:15:0003/26/2022 | Carolina Skyhawks | 40 - 37 | Atlanta Swarm | N/A |
| 2022-03-26 19:20:0003/26/2022 | Tulsa Desperados | 17 - 48 | Florida Storm | N/A |
| 2022-03-26 21:00:0003/26/2022 | San Diego Mavericks | 21 - 43 | Houston Hyenas | N/A |
| 2022-03-27 19:00:0003/27/2022 | Las Vegas Fury | 17 - 28 | Baltimore Vultures | N/A |
| 2022-03-27 21:20:0003/27/2022 | Queen City Corsairs | 17 - 41 | Sioux Falls Sparrows | N/A |
| 2022-03-28 19:15:0003/28/2022 | Fort Worth Toros | 24 - 30 | Lone Star Glory | N/A |
| 2022-04-02 14:30:0004/02/2022 | Atlanta Swarm | 30 - 41 | Florida Storm | N/A |
| 2022-04-02 15:00:0004/02/2022 | Denver Nightwings | 38 - 30 | Queen City Corsairs | N/A |
| 2022-04-02 16:45:0004/02/2022 | Houston Hyenas | 34 - 41 | Mexico City Aztecs | N/A |
| 2022-04-02 17:15:0004/02/2022 | San Diego Mavericks | 21 - 27 | Portland Fleet | N/A |
| 2022-04-02 21:20:0004/02/2022 | Arizona Scorpions | 23 - 30 | Las Vegas Fury | N/A |
| 2022-04-03 19:00:0004/03/2022 | Baltimore Vultures | 17 - 24 | D.C. Dragons | N/A |
| 2022-04-03 19:20:0004/03/2022 | Louisiana Revolution | 28 - 31 | Jacksonville Kings | N/A |
| 2022-04-03 21:00:0004/03/2022 | Charleston Predators | 14 - 38 | St. Louis Gladiators | N/A |
| 2022-04-09 12:00:0004/09/2022 | Charleston Predators | 44 - 27 | Atlanta Swarm | N/A |
| 2022-04-09 12:20:0004/09/2022 | Queen City Corsairs | 31 - 34 | London Knights | N/A |
| 2022-04-09 14:30:0004/09/2022 | Las Vegas Fury | 25 - 24 | D.C. Dragons | N/A |
| 2022-04-09 15:00:0004/09/2022 | Los Angeles Lycans | 23 - 38 | Mexico City Aztecs | N/A |
| 2022-04-09 16:45:0004/09/2022 | Baltimore Vultures | 32 - 35 | Arizona Scorpions | N/A |
| 2022-04-09 17:15:0004/09/2022 | Florida Storm | 33 - 21 | Jacksonville Kings | N/A |
| 2022-04-09 17:20:0004/09/2022 | Sioux Falls Sparrows | 27 - 24 | Denver Nightwings | N/A |
| 2022-04-09 20:00:0004/09/2022 | Houston Hyenas | 24 - 30 | Vancouver Legion | N/A |
| 2022-04-10 12:00:0004/10/2022 | Carolina Skyhawks | 12 - 20 | St. Louis Gladiators | N/A |
| 2022-04-10 19:00:0004/10/2022 | Portland Fleet | 35 - 30 | Fort Worth Toros | N/A |
| 2022-04-10 19:20:0004/10/2022 | Louisiana Revolution | 23 - 28 | Tulsa Desperados | N/A |
| 2022-04-10 21:00:0004/10/2022 | Lone Star Glory | 35 - 28 | San Diego Mavericks | N/A |
| 2022-04-15 12:20:0004/15/2022 | Fort Worth Toros | 31 - 24 | Houston Hyenas | N/A |
| 2022-04-15 14:30:0004/15/2022 | Los Angeles Lycans | 34 - 32 | Portland Fleet | N/A |
| 2022-04-15 15:00:0004/15/2022 | Queen City Corsairs | 27 - 30 | Baltimore Vultures | N/A |
| 2022-04-15 16:45:0004/15/2022 | Las Vegas Fury | 45 - 34 | Denver Nightwings | N/A |
| 2022-04-15 17:20:0004/15/2022 | Vancouver Legion | 34 - 27 | San Diego Mavericks | N/A |
| 2022-04-15 19:00:0004/15/2022 | St. Louis Gladiators | 17 - 24 | Louisiana Revolution | N/A |
| 2022-04-15 19:20:0004/15/2022 | Atlanta Swarm | 21 - 45 | Tulsa Desperados | N/A |
| 2022-04-15 21:00:0004/15/2022 | Arizona Scorpions | 38 - 27 | Sioux Falls Sparrows | N/A |
| 2022-04-16 12:00:0004/16/2022 | Jacksonville Kings | 49 - 55 | Carolina Skyhawks | N/A |
| 2022-04-16 17:00:0004/16/2022 | D.C. Dragons | 16 - 27 | London Knights | N/A |
| 2022-04-16 17:15:0004/16/2022 | Florida Storm | 24 - 29 | Charleston Predators | N/A |
| 2022-04-16 21:20:0004/16/2022 | Mexico City Aztecs | 27 - 33 | Lone Star Glory | N/A |
| 2022-04-23 14:30:2704/23/2022 | Jacksonville Kings | 21 - 34 | London Knights | N/A |
| 2022-04-23 14:45:2704/23/2022 | Mexico City Aztecs | 34 - 44 | Charleston Predators | N/A |
| 2022-04-24 14:30:2704/24/2022 | Tulsa Desperados | 36 - 21 | D.C. Dragons | N/A |
| 2022-04-24 14:45:5004/24/2022 | Florida Storm | 17 - 31 | Sioux Falls Sparrows | N/A |
| 2022-04-30 14:15:2104/30/2022 | Tulsa Desperados | 10 - 24 | Vancouver Legion | N/A |
| 2022-04-30 16:45:3204/30/2022 | Sioux Falls Sparrows | 21 - 34 | Lone Star Glory | N/A |
| 2022-05-01 10:00:3805/01/2022 | London Knights | 14 - 43 | Baltimore Vultures | N/A |
| 2022-05-01 15:00:0005/01/2022 | Charleston Predators | 27 - 45 | Louisiana Revolution | N/A |
| 2022-05-08 06:10:4005/08/2022 | Louisiana Revolution | 7 - 34 | Baltimore Vultures | N/A |
| 2022-05-08 06:11:2305/08/2022 | Lone Star Glory | 20 - 17 | Vancouver Legion | N/A |
| 2022-05-14 15:00:1605/14/2022 | Lone Star Glory | 24 - 38 | Baltimore Vultures | N/A |
